PTBP1 is required for glucose-stimulated cap-independent translation of insulin granule proteins and Coxsackieviruses in beta cells

Glucose and GLP-1 stimulate not only insulin secretion, but also the post-transcriptional induction of insulin granule biogenesis. This process involves the nucleocytoplasmic translocation of the RNA binding protein PTBP1. Binding of PTBP1 to the 3′-UTRs of mRNAs for insulin and other cargoes of bet...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Knoch, Klaus-Peter, Nath-Sain, Suchita, Petzold, Antje, Schneider, Hendryk, Beck, Mike, Wegbrod, Carolin, Sönmez, Anke, Münster, Carla, Friedrich, Anne, Roivainen, Merja, Solimena, Michele
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Elsevier 2014
विषय:
Original Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4099505/
https://ncbi.nlm.nih.gov/pubmed/25061557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2014.05.002
टैग : टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!

समान संसाधन