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Coxsackievirus A9 VP1 Mutants with Enhanced or Hindered A Particle Formation and Decreased Infectivity

We have studied coxsackievirus A9 (CAV9) mutants that each have a single amino acid substitution in the conserved 29-PALTAVETGHT-39 motif of VP1 and a reduced capacity to produce infectious progeny virus. After uncoating, all steps in the infection cycle occurred according to the same kinetics as an...

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Main Authors: Airaksinen, Antero, Roivainen, Merja, Hovi, Tapani
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2001
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC113991/
https://ncbi.nlm.nih.gov/pubmed/11134308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.2.952-960.2001
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