Cleavage of VP1 and modification of antigenic site 1 of type 2 polioviruses by intestinal trypsin.

We have exposed 22 independent type 2 poliovirus isolates to human intestinal fluid and purified trypsin. In all cases the virus retained its infectivity, while polyacrylamide gel electrophoresis of viral proteins showed disappearance of the VP1 bands. Concomitantly, the viruses became resistant to...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Roivainen, M, Hovi, T
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1988
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC253485/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2841503/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.62.9.3536-3539.1988
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