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Functions of Caspase 8: the Identified and the Mysterious

Initially discovered as an initiator protease in apoptosis mediated by death receptors, caspase-8 is now known to have an apparently confounding opposing effect in securing cell survival. It is required to allow mouse embryo survival, and the survival of hematopoietic cells during their development...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Salvesen, Guy S., Walsh, Craig M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4099255/
https://ncbi.nlm.nih.gov/pubmed/24856110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2014.03.005
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