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RIPK-dependent necrosis and its regulation by caspases: A mystery in five acts

Caspase-8, FADD, and FLIP orchestrate apoptosis in response to death receptor ligation. Mysteriously however, these proteins are also required for normal embryonic development and immune cell proliferation, an observation that has led to their implication in several non-apoptotic processes. While ma...

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Autors principals: Green, Douglas R., Oberst, Andrew, Dillon, Christopher P., Weinlich, Ricardo, Salvesen, Guy S.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192321/
https://ncbi.nlm.nih.gov/pubmed/21981915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.09.003
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