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RIPK-dependent necrosis and its regulation by caspases: A mystery in five acts

Caspase-8, FADD, and FLIP orchestrate apoptosis in response to death receptor ligation. Mysteriously however, these proteins are also required for normal embryonic development and immune cell proliferation, an observation that has led to their implication in several non-apoptotic processes. While ma...

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Detalhes bibliográficos
Main Authors: Green, Douglas R., Oberst, Andrew, Dillon, Christopher P., Weinlich, Ricardo, Salvesen, Guy S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192321/
https://ncbi.nlm.nih.gov/pubmed/21981915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.09.003
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