DUX4, a Candidate Gene for Facioscapulohumeral Muscular Dystrophy, Causes p53-Dependent Myopathy In Vivo

OBJECTIVE: Facioscapulohumeral muscular dystrophy (FSHD) is associated with D4Z4 repeat contraction on human chromosome 4q35. This genetic lesion does not result in complete loss or mutation of any gene. Consequently, the pathogenic mechanisms underlying FSHD have been difficult to discern. In leadi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Wallace, Lindsay M., Garwick, Sara E., Mei, Wenyan, Belayew, Alexandra, Coppee, Frederique, Ladner, Katherine J., Guttridge, Denis, Yang, Jing, Harper, Scott Q.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4098764/
https://ncbi.nlm.nih.gov/pubmed/21446026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.22275
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados