The Cholesterol Metabolite 27-Hydroxycholesterol Promotes Atherosclerosis via Proinflammatory Processes Mediated by Estrogen Receptor Alpha

Oxysterols are cholesterol metabolites that serve multiple functions in lipid metabolism, including as liver X receptor (LXR) ligands. 27-hydroxycholesterol (27HC) is an abundant oxysterol metabolized by CYP7B1. How 27HC impacts vascular health is unknown. We show that elevations in 27HC via cyp7b1...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Umetani, Michihisa, Ghosh, Pritam, Ishikawa, Tomonori, Umetani, Junko, Ahmed, Mohamed, Mineo, Chieko, Shaul, Philip W.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4098728/
https://ncbi.nlm.nih.gov/pubmed/24954418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2014.05.013
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars