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27-Hydroxycholesterol Is an Endogenous Selective Estrogen Receptor Modulator

Selective estrogen receptor (ER) modulators (SERMs) are ER ligands whose relative agonist/antagonist activities vary in a cell- and promoter-dependent manner. The molecular basis underlying this selectivity can be attributed to the ability of these ligands to induce distinct alterations in ER struct...

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Autors principals: DuSell, Carolyn D., Umetani, Michihisa, Shaul, Philip W., Mangelsdorf, David J., McDonnell, Donald P.
Format: Artigo
Idioma:Inglês
Publicat: The Endocrine Society 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194632/
https://ncbi.nlm.nih.gov/pubmed/17872378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2007-0383
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