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27-Hydroxycholesterol: the First Identified Endogenous SERM
The cholesterol metabolite 27-hydroxycholesterol (27HC) classically delivers sterols from peripheral tissues to the liver and is a substrate for bile acid synthesis. Recent studies have revealed that 27HC also uniquely binds to and modifies estrogen receptor (ER) α and ERβ function. Experiments in m...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3070823/ https://ncbi.nlm.nih.gov/pubmed/21353593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2011.01.003 |
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