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SUN-016 27-Hydroxycholesterol a Selective Estrogen Receptor Modulator: Profiling 27-Hydroxycholesterol Effects on Estrogen Receptor Activity in Mice

27-Hydroxycholesterol (27-HC) is the most prevalent metabolite of cholesterol in circulation, and also the first identified endogenous selective estrogen receptor (ER) modulator (SERM) (1). Previously, we found that 27-HC acts as an agonist of ER in breast cancer cells, while it acts as an antagonis...

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Bibliografiset tiedot
Julkaisussa:J Endocr Soc
Päätekijät: Asghari, Arvand, Hiramitsu, Shiro, Dao, Kevin, Umetani, Michihisa
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Endocrine Society 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6553081/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SUN-016
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