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Ubiquitin conjugation by the N-end rule pathway and mRNAs for its components increase in muscles of diabetic rats
Insulin deficiency (e.g., in acute diabetes or fasting) is associated with enhanced protein breakdown in skeletal muscle leading to muscle wasting. Because recent studies have suggested that this increased proteolysis is due to activation of the ubiquitin-proteasome (Ub-proteasome) pathway, we inves...
Shranjeno v:
| izdano v: | J Clin Invest |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Clinical Investigation
1999
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC409840/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10562303/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI7300 |
| Oznake: |
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