The N-end rule is mediated by the UBC2(RAD6) ubiquitin-conjugating enzyme.
The N-end rule relates the in vivo half-life of a protein to the identity of its amino-terminal residue. Distinct versions of the N-end rule operate in all organisms examined, from mammals to bacteria. We show that UBC2(RAD6), one of at least seven ubiquitin-conjugating enzymes in the yeast Saccharo...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1991
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52293/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1651502/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.16.7351 |
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