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The N-end rule is mediated by the UBC2(RAD6) ubiquitin-conjugating enzyme.

The N-end rule relates the in vivo half-life of a protein to the identity of its amino-terminal residue. Distinct versions of the N-end rule operate in all organisms examined, from mammals to bacteria. We show that UBC2(RAD6), one of at least seven ubiquitin-conjugating enzymes in the yeast Saccharo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dohmen, R J, Madura, K, Bartel, B, Varshavsky, A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1991
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC52293/
https://ncbi.nlm.nih.gov/pubmed/1651502
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