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Evaluating N-benzylgalactonoamidines as putative transition state analogs for β-galactoside hydrolysis
Experimental evidence is provided for p-methylbenzyl-D-galactonoamidine to function as a true transition state analog for the enzymatic hydrolysis of aryl-β-D-galactopyranosides by β-galactosidase (A. oryzae). The compound exhibits inhibition constants in the low nanomolar concentration range (12–56...
Gorde:
| Egile Nagusiak: | , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2014
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4096895/ https://ncbi.nlm.nih.gov/pubmed/24668069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4ob00153b |
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