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Resilience of precuneus neurotrophic signaling pathways despite amyloid pathology in prodromal Alzheimer's disease
BACKGROUND: Precuneus choline acetytransferase activity reduction co-occurs with greater β-amyloid (Aβ) in Alzheimer's disease (AD). Whether this cholinergic deficit associates with alterations in nerve growth factor (NGF) signaling and its relation to Aβ plaque and neurofibrillary tangle (NFT)...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4096429/ https://ncbi.nlm.nih.gov/pubmed/24529280 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2013.12.016 |
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