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Precuneus amyloid burden is associated with reduced cholinergic activity in Alzheimer disease
OBJECTIVE: This study examined the relationship between postmortem precuneus cholinergic enzyme activity, Pittsburgh compound B (PiB) binding, and soluble amyloid-β concentration in mild cognitive impairment (MCI) and Alzheimer disease (AD). METHODS: Choline acetyltransferase (ChAT) activity, [(3)H]...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Lippincott Williams & Wilkins
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3127332/ https://ncbi.nlm.nih.gov/pubmed/21700583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e3182231419 |
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