Cortical α7 Nicotinic Acetylcholine Receptor and β-Amyloid Levels in Early Alzheimer’s Disease

OBJECTIVE: To examine α7 nicotinic acetylcholine receptor (nAChR) binding and β-amyloid (Aβ) peptide load in superior frontal cortex (SFC) across clinical and neuropathological stages of Alzheimer’s disease (AD). DESIGN: Quantitative measures of α7 nAChR by [(3)H]methyllycaconitine binding and Aβ co...

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Autori principali: Ikonomovic, Milos D., Wecker, Lynn, Abrahamson, Eric E., Wuu, Joanne, Counts, Scott, Ginsberg, Stephan, Mufson, Elliott, DeKosky, Steven T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841566/
https://ncbi.nlm.nih.gov/pubmed/19433665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archneurol.2009.46
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