Hydrogel-Based 3D Model of Patient-Derived Prostate Xenograft Tumors Suitable for Drug Screening

[Image: see text] The lack of effective therapies for bone metastatic prostate cancer (PCa) underscores the need for accurate models of the disease to enable the discovery of new therapeutic targets and to test drug sensitivities of individual tumors. To this end, the patient-derived xenograft (PDX)...

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Main Authors: Fong, Eliza L. S., Martinez, Mariane, Yang, Jun, Mikos, Antonios G., Navone, Nora M., Harrington, Daniel A., Farach-Carson, Mary C.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2014
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096229/
https://ncbi.nlm.nih.gov/pubmed/24779589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp500085p
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