Recreating the Tumor Microenvironment in a Bilayer, Hyaluronic Acid Hydrogel Construct for the Growth of Prostate Cancer Spheroids

Cancer cells cultured in physiologically relevant, three-dimensional (3D) matrices can recapture many essential features of native tumor tissues. In this study, a hyaluronic acid (HA)-based bilayer hydrogel system that not only supports the tumoroid formation from LNCaP prostate cancer (PCa) cells,...

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Autors principals: Xu, Xian, Gurski, Lisa A., Zhang, Chu, Harrington, Daniel A., Farach-Carson, Mary C., Jia, Xinqiao
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466381/
https://ncbi.nlm.nih.gov/pubmed/22999468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2012.08.061
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