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Hyaluronic Acid-Based Hydrogels as 3D Matrices for in Vitro Evaluation of Chemotherapeutic Drugs Using Poorly Adherent Prostate Cancer Cells

The current investigation aimed to develop a biomimetic, three-dimensional (3D) culture system for poorly adherent bone metastatic prostate cancer cells (C4-2B) for use as an in vitro platform for anti-cancer drug screening. To this end, hyaluronic acid (HA) derivatives carrying complementary aldehy...

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Detalles Bibliográficos
Main Authors: Gurski, Lisa A., Jha, Amit K., Zhang, Chu, Jia, Xinqiao, Farach-Carson, Mary C.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782556/
https://ncbi.nlm.nih.gov/pubmed/19695694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2009.07.054
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