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Three–dimensional (3D) culture of bone–derived human 786–O renal cell carcinoma retains relevant clinical characteristics of bone metastases
Bone metastases from renal cell carcinoma (RCC) are typically lytic, destructive, and resistant to treatment regimens. Current in vitro models for studying metastasis introduce artifacts that limit their usefulness. Many features of tumors growing in bone are lost when human RCC cells are cultured i...
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| Publicado no: | Cancer Lett |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4530612/ https://ncbi.nlm.nih.gov/pubmed/26004343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2015.05.019 |
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