Sustained delivery of recombinant human bone morphogenetic protein-2 from perlecan domain I - functionalized electrospun poly (ε-caprolactone) scaffolds for bone regeneration

BACKGROUND: Biomaterial scaffolds that deliver growth factors such as recombinant human bone morphogenetic proteins-2 (rhBMP-2) have improved clinical bone tissue engineering by enhancing bone tissue regeneration. This approach could be further improved if the controlled delivery of bioactive rhBMP-...

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Detalhes bibliográficos
Publicado no:J Exp Orthop
Main Authors: Chiu, Yu-Chieh, Fong, Eliza L., Grindel, Brian J., Kasper, Fred K., Harrington, Daniel A., Farach-Carson, Mary C.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053971/
https://ncbi.nlm.nih.gov/pubmed/27714703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40634-016-0057-1
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