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Activity and Architecture of Pyroglutamate-Modified Amyloid-β (Aβ(pE3-42)) Pores
[Image: see text] Among the family of Aβ peptides, pyroglutamate-modified Aβ (Aβ(pE)) peptides are particularly associated with cytotoxicity in Alzheimer’s disease (AD). They represent the dominant fraction of Aβ oligomers in the brains of AD patients, but their accumulation in the brains of elderly...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Chemical
Society
2014
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4096221/ https://ncbi.nlm.nih.gov/pubmed/24922585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp5040954 |
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