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Mechanisms for the Insertion of Toxic, Fibril-like β-Amyloid Oligomers into the Membrane
Amyloid-β (Aβ) oligomers destabilize cellular ionic homeostasis, mediating Alzheimer's disease (AD). It is still unclear whether the mechanism (i) is mediated by cell surface receptors; (ii) is direct, with Aβ oligomers interacting with membrane lipids; or (iii) both mechanisms take place. Rece...
Tallennettuna:
| Päätekijät: | , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2012
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3539805/ https://ncbi.nlm.nih.gov/pubmed/23316126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ct300916f |
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