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Disordered amyloidogenic peptides may insert into the membrane and assemble into common cyclic structural motifs
Aggregation of disordered amyloidogenic peptides into oligomers is the causative agent of amyloid-related diseases. In solution, disordered protein states are characterized by heterogeneous ensembles. Among these, β-rich conformers self-assemble via a conformational selection mechanism to form energ...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4143503/ https://ncbi.nlm.nih.gov/pubmed/24566672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3cs60459d |
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