Undecaprenyl Diphosphate Synthase Inhibitors: Antibacterial Drug Leads

[Image: see text] There is a significant need for new antibiotics due to the rise in drug resistance. Drugs such as methicillin and vancomycin target bacterial cell wall biosynthesis, but methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE) have now arisen an...

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Bibliographic Details
Main Authors: Sinko, William, Wang, Yang, Zhu, Wei, Zhang, Yonghui, Feixas, Ferran, Cox, Courtney L., Mitchell, Douglas A., Oldfield, Eric, McCammon, J. Andrew
Format: Artigo
Language:Inglês
Published: American Chemical Society 2014
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096218/
https://ncbi.nlm.nih.gov/pubmed/24827744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm5004649
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