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B cell Toll-like receptors and immunoglobulin class-switch DNA recombination

Toll-like receptors (TLRs) are a family of conserved pattern recognition receptors (PRRs). Engagement of TLRs in B cells by microbe-associated molecular patterns (MAMPs) induces T-independent (TI) antibody responses and plays an important role in the early stages of T-dependent (TD) antibody respons...

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Autori principali: Pone, Egest J., Xu, Zhenming, White, Clayton A., Zan, Hong, Casali, Paolo
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4095906/
https://ncbi.nlm.nih.gov/pubmed/22652800
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