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Toll-like Receptors and B-cell Receptors Synergize to Induce Immunoglobulin Class Switch DNA Recombination: Relevance to Microbial Antibody Responses

Differentiation of naïve B cells, including immunoglobulin (Ig) class switch DNA recombination (CSR), is critical for the immune response and depends on the extensive integration of signals from the B cell receptor (BCR), tumor necrosis factor (TNF) receptor family members, Toll-like receptors (TLRs...

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Autors principals: Pone, Egest J., Zan, Hong, Zhang, Jinsong, Al-Qahtani, Ahmed, Xu, Zhenming, Casali, Paolo
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038989/
https://ncbi.nlm.nih.gov/pubmed/20370617
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