Sirtuin 1 Enzymatic Activity Is Required for Cartilage Homeostasis In Vivo in a Mouse Model

Eitemau Tebyg

• Sirt1-deficient mice exhibit an altered cartilage phenotype
  gan: Gabay, Odile, et al.
  Cyhoeddwyd: (2013)
• Increased Apopototic Chondrocytes in Articular Cartilage of Adults Heterozygous SirT1 Mice
  gan: Gabay, Odile, et al.
  Cyhoeddwyd: (2012)
• Regulation of Cartilage-specific Gene Expression in Human Chondrocytes by SirT1 and Nicotinamide Phosphoribosyltransferase
  gan: Dvir-Ginzberg, Mona, et al.
  Cyhoeddwyd: (2008)
• Tumor Necrosis Factor α–Mediated Cleavage and Inactivation of SirT1 in Human Osteoarthritic Chondrocytes
  gan: Dvir-Ginzberg, Mona, et al.
  Cyhoeddwyd: (2011)
• SirT1 enhances survival of human osteoarthritic chondrocytes by repressing PTP1B and activating the IGF receptor pathway
  gan: Gagarina, Viktoria, et al.
  Cyhoeddwyd: (2010)