Resistance to the mTOR Inhibitor Temsirolimus Alters Adhesion and Migration Behavior of Renal Cell Carcinoma Cells through an Integrin α5– and Integrin β3–Dependent Mechanism()()

Inhibitors of the mammalian target of rapamycin (mTOR) have improved the treatment of renal cell carcinoma (RCC). However, chronic drug exposure may trigger resistance, limiting the utility of these agents. The metastatic behavior of RCC cells, susceptible (RCC(par)) or resistant (RCC(res)) to the m...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Juengel, Eva, Makarević, Jasmina, Reiter, Michael, Mani, Jens, Tsaur, Igor, Bartsch, Georg, Haferkamp, Axel, Blaheta, Roman A.
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094828/
https://ncbi.nlm.nih.gov/pubmed/24862756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2014.03.011
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados