Загрузка...
Resistance to the mTOR Inhibitor Temsirolimus Alters Adhesion and Migration Behavior of Renal Cell Carcinoma Cells through an Integrin α5– and Integrin β3–Dependent Mechanism
Inhibitors of the mammalian target of rapamycin (mTOR) have improved the treatment of renal cell carcinoma (RCC). However, chronic drug exposure may trigger resistance, limiting the utility of these agents. The metastatic behavior of RCC cells, susceptible (RCCpar) or resistant (RCCres) to the mTOR...
Сохранить в:
| Главные авторы: | , , , , , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Elsevier
2014-04-01
|
| Серии: | Neoplasia: An International Journal for Oncology Research |
| Online-ссылка: | http://www.sciencedirect.com/science/article/pii/S147655861400030X |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|