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HDAC inhibition as a treatment concept to combat temsirolimus-resistant bladder cancer cells
INTRODUCTION: Although the mechanistic target of rapamycin (mTOR) might be a promising molecular target to treat advanced bladder cancer, resistance develops under chronic exposure to an mTOR inhibitor (everolimus, temsirolimus). Based on earlier studies, we proposed that histone deacetylase (HDAC)...
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| 發表在: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Impact Journals LLC
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5746361/ https://ncbi.nlm.nih.gov/pubmed/29299126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22454 |
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