The DNA repair component Metnase regulates Chk1 stability

Chk1 both arrests replication forks and enhances repair of DNA damage by phosphorylation of downstream effectors. Metnase (also termed SETMAR) is a SET histone methylase and transposase nuclease protein that promotes both DNA double strand break (DSB) repair and re-start of stalled replication forks...

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Autores principales: Williamson, Elizabeth A, Wu, Yuehan, Singh, Sudha, Byrne, Michael, Wray, Justin, Lee, Suk-Hee, Nickoloff, Jac A, Hromas, Robert
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
Materias:
Short Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094783/
https://ncbi.nlm.nih.gov/pubmed/25024738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1747-1028-9-1
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