Benzimidazoles: Novel Mycobacterial Gyrase Inhibitors from Scaffold Morphing

[Image: see text] Type II topoisomerases are well conserved across the bacterial species, and inhibition of DNA gyrase by fluoroquinolones has provided an attractive option for treatment of tuberculosis (TB). However, the emergence of fluoroquinolone-resistant strains of Mycobacterium tuberculosis (...

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Hlavní autoři: Hameed P, Shahul, Raichurkar, Anandkumar, Madhavapeddi, Prashanti, Menasinakai, Sreenivasaiah, Sharma, Sreevalli, Kaur, Parvinder, Nandishaiah, Radha, Panduga, Vijender, Reddy, Jitendar, Sambandamurthy, Vasan K., Sriram, D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2014
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094266/
https://ncbi.nlm.nih.gov/pubmed/25050172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml5001728
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