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Enantioselective Synthesis of Boron-Substituted Quaternary Carbon Stereogenic Centers through NHC–Catalyzed Conjugate Additions of (Pinacolato)boron Units to Enones()

The first examples of Lewis base-catalyzed enantioselective boryl conjugate additions (BCA) that generate boron-substituted quaternary carbon stereogenic centers are disclosed. Reactions are performed in the presence of 1.0–5.0 mol % of a readily available chiral accessible N-heterocyclic carbene (N...

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Bibliografiska uppgifter
Huvudupphovsmän: Radomkit, Suttipol, Hoveyda, Amir H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094110/
https://ncbi.nlm.nih.gov/pubmed/24615958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201309982
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