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Insulin Receptor Activation with Transmembrane Domain Ligands
Complementary surfaces are buried when peptide hormones, growth factors, or cytokines bind and activate cellular receptors. Although these extended surfaces provide high affinity and specificity to the interactions, they also present great challenges to the design of small molecules that might eithe...
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| Hoofdauteurs: | , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Biochemistry and Molecular Biology
2014
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4094086/ https://ncbi.nlm.nih.gov/pubmed/24867955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.578641 |
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