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The Antibodies against the Computationally Designed Mimic of the Glycoprotein Hormone Receptor Transmembrane Domain Provide Insights into Receptor Activation and Suppress the Constitutively Activated Receptor Mutants

The exoloops of glycoprotein hormone receptors (GpHRs) transduce the signal generated by the ligand-ectodomain interactions to the transmembrane helices either through direct hormonal contact and/or by modulating the interdomain interactions between the hinge region (HinR) and the transmembrane doma...

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Detalles Bibliográficos
Main Authors: Majumdar, Ritankar, Railkar, Reema, Dighe, Rajan R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464559/
https://ncbi.nlm.nih.gov/pubmed/22904318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.355032
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