Molecular Cloning and Functional Characterization of Components of the Capsule Biosynthesis Complex of Neisseria meningitidis Serogroup A: TOWARD IN VITRO VACCINE PRODUCTION

The human pathogen Neisseria meningitidis (Nm) is a leading cause of bacterial meningitis and sepsis globally. A major virulence factor of Nm is the capsular polysaccharide (CPS), which in Nm serogroup A consists of N-acetyl-mannosamine-1-phosphate units linked together by phosphodiester linkages [→...

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Detalhes bibliográficos
Main Authors: Fiebig, Timm, Freiberger, Friedrich, Pinto, Vittoria, Romano, Maria Rosaria, Black, Alan, Litschko, Christa, Bethe, Andrea, Yashunsky, Dmitry, Adamo, Roberto, Nikolaev, Andrei, Berti, Francesco, Gerardy-Schahn, Rita
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4094051/
https://ncbi.nlm.nih.gov/pubmed/24849599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.575142
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