Protein Interferon-Stimulated Gene 15 Conjugation Delays but Does Not Overcome Coronavirus Proliferation in a Model of Fulminant Hepatitis

Coronaviruses express a deubiquitinating protein, the papain-like protease-2 (PLP2), that removes both ubiquitin and the ubiquitin-like interferon (IFN)-stimulated gene 15 (ISG15) protein from target proteins. ISG15 has antiviral activity against a number of viruses; therefore, we examined the effec...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Ma, Xue-Zhong, Bartczak, Agata, Zhang, Jianhua, He, Wei, Shalev, Itay, Smil, David, Chen, Limin, Phillips, Jim, Feld, Jordan J., Selzner, Nazia, Levy, Gary, McGilvray, Ian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4093886/
https://ncbi.nlm.nih.gov/pubmed/24648452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03801-13
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados