Proteasome Inhibition In Vivo Promotes Survival in a Lethal Murine Model of Severe Acute Respiratory Syndrome

Ubiquitination is a critical regulator of the host immune response to viral infection, and many viruses, including coronaviruses, encode proteins that target the ubiquitination system. To explore the link between coronavirus infection and the ubiquitin system, we asked whether protein degradation by...

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Main Authors: Ma, Xue-Zhong, Bartczak, Agata, Zhang, Jianhua, Khattar, Ramzi, Chen, Limin, Liu, Ming Feng, Edwards, Aled, Levy, Gary, McGilvray, Ian D.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2010
Assuntos:
Virus-Cell Interactions
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976395/
https://ncbi.nlm.nih.gov/pubmed/20861244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01219-10
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