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Animal Model of Respiratory Syncytial Virus: CD8(+) T Cells Cause a Cytokine Storm That Is Chemically Tractable by Sphingosine-1-Phosphate 1 Receptor Agonist Therapy

The cytokine storm is an intensified, dysregulated, tissue-injurious inflammatory response driven by cytokine and immune cell components. The cytokine storm during influenza virus infection, whereby the amplified innate immune response is primarily responsible for pulmonary damage, has been well cha...

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Detalhes bibliográficos
Main Authors: Walsh, Kevin B., Teijaro, John R., Brock, Linda G., Fremgen, Daniel M., Collins, Peter L., Rosen, Hugh, Oldstone, Michael B. A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4093868/
https://ncbi.nlm.nih.gov/pubmed/24672024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00464-14
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