Animal Model of Respiratory Syncytial Virus: CD8(+) T Cells Cause a Cytokine Storm That Is Chemically Tractable by Sphingosine-1-Phosphate 1 Receptor Agonist Therapy

The cytokine storm is an intensified, dysregulated, tissue-injurious inflammatory response driven by cytokine and immune cell components. The cytokine storm during influenza virus infection, whereby the amplified innate immune response is primarily responsible for pulmonary damage, has been well cha...

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Bibliografiska uppgifter
Huvudupphovsmän: Walsh, Kevin B., Teijaro, John R., Brock, Linda G., Fremgen, Daniel M., Collins, Peter L., Rosen, Hugh, Oldstone, Michael B. A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2014
Ämnen:
Pathogenesis and Immunity
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4093868/
https://ncbi.nlm.nih.gov/pubmed/24672024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00464-14
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