Three Phases of CD8 T Cell Response in the Lung Following H1N1 Influenza Infection and Sphingosine 1 Phosphate Agonist Therapy

Influenza-induced lung edema and inflammation are exacerbated by a positive feedback loop of cytokine and chemokine production termed a ‘cytokine storm’, a hallmark of increased influenza-related morbidity and mortality. Upon infection, an immune response is rapidly initiated in the lungs and draini...

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Detalhes bibliográficos
Main Authors: Matheu, Melanie P., Teijaro, John R., Walsh, Kevin B., Greenberg, Milton L., Marsolais, David, Parker, Ian, Rosen, Hugh, Oldstone, Michael B A., Cahalan, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606384/
https://ncbi.nlm.nih.gov/pubmed/23533579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058033
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