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Mapping the innate signaling cascade essential for cytokine storm during influenza virus infection

During pathogenic influenza virus infection, robust cytokine production (cytokine storm), excessive inflammatory infiltrates, and virus-induced tissue destruction all contribute to morbidity and mortality. Earlier we reported that modulation of sphingosine-1-phosphate-1 receptor (S1P(1)R) signaling...

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Detalhes bibliográficos
Main Authors: Teijaro, John R., Walsh, Kevin B., Rice, Stephanie, Rosen, Hugh, Oldstone, Michael B. A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3956176/
https://ncbi.nlm.nih.gov/pubmed/24572573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1400593111
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