Activation of Kaposi's Sarcoma-Associated Herpesvirus (KSHV) by Inhibitors of Class III Histone Deacetylases: Identification of Sirtuin 1 as a Regulator of the KSHV Life Cycle

Kaposi's sarcoma-associated herpesvirus (KSHV) establishes persistent latent infection in immunocompetent hosts. Disruption of KSHV latency results in viral lytic replication, which promotes the development of KSHV-related malignancies in immunocompromised individuals. While inhibitors of class...

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Detalhes bibliográficos
Main Authors: Li, Qiuhua, He, Meilan, Zhou, Fuchun, Ye, Fengchun, Gao, Shou-Jiang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4093851/
https://ncbi.nlm.nih.gov/pubmed/24672028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00219-14
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