Short-Chain Fatty Acids from Periodontal Pathogens Suppress Histone Deacetylases, EZH2, and SUV39H1 To Promote Kaposi's Sarcoma-Associated Herpesvirus Replication

Periodontal pathogens such as Porphyromonas gingivalis and Fusobacterium nucleatum produce five different short-chain fatty acids (SCFAs) as metabolic by-products. We detect significantly higher levels of SCFAs in the saliva of patients with severe periodontal disease. The different SCFAs stimulate...

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Detalhes bibliográficos
Main Authors: Yu, Xiaolan, Shahir, Abdel-Malek, Sha, Jingfeng, Feng, Zhimin, Eapen, Betty, Nithianantham, Stanley, Das, Biswajit, Karn, Jonathan, Weinberg, Aaron, Bissada, Nabil F., Ye, Fengchun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993761/
https://ncbi.nlm.nih.gov/pubmed/24501407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03326-13
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