Alternative splicing regulates the expression of G9A and SUV39H2 methyltransferases, and dramatically changes SUV39H2 functions

Alternative splicing is the main source of proteome diversity. Here, we have investigated how alternative splicing affects the function of two human histone methyltransferases (HMTase): G9A and SUV39H2. We show that exon 10 in G9A and exon 3 in SUV39H2 are alternatively included in a variety of tiss...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Mauger, Oriane, Klinck, Roscoe, Chabot, Benoit, Muchardt, Christian, Allemand, Eric, Batsché, Eric
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2015
Fag:
RNA
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4330376/
https://ncbi.nlm.nih.gov/pubmed/25605796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv013
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