Downregulation of Histone Methyltransferase Genes SUV39H1 and SUV39H2 Increases Telomere Length in Embryonic Stem-like Cells and Embryonic Fibroblasts in Pigs

Telomere is a nucleoprotein structure at the ends of chromosomes that helps to protect the ends of chromosomes from being fused with other chromosomes. Knockout of histone methyltransferases Suv39h1 and Suv39h2 increases the telomere length in murine cells, whereas downregulation of SUV39H1 and SUV3...

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Detalhes bibliográficos
Main Authors: DANG-NGUYEN, Thanh Quang, HARAGUCHI, Seiki, FURUSAWA, Tadashi, SOMFAI, Tamas, KANEDA, Masahiro, WATANABE, Shinya, AKAGI, Satoshi, KIKUCHI, Kazuhiro, TAJIMA, Atsushi, NAGAI, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: The Society for Reproduction and Development 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943233/
https://ncbi.nlm.nih.gov/pubmed/23018532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1262/jrd.2012-118
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