Kaposi's Sarcoma-Associated Herpesvirus (KSHV) Latency-Associated Nuclear Antigen Regulates the KSHV Epigenome by Association with the Histone Demethylase KDM3A

Kaposi's sarcoma-associated herpesvirus (KSHV) latent genomes are tethered to host histones to form a minichromosome also known as an “episome.” Histones, which are core components of chromatin, are heavily modified by various histone-targeting enzymes. Posttranslational modifications of histon...

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Hlavní autoři: Kim, Kevin Y., Huerta, Steve B., Izumiya, Chie, Wang, Don-Hong, Martinez, Anthony, Shevchenko, Bogdan, Kung, Hsing-Jien, Campbell, Mel, Izumiya, Yoshihiro
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
Témata:
Genome Replication and Regulation of Viral Gene Expression
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676133/
https://ncbi.nlm.nih.gov/pubmed/23576503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00011-13
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