Kaposi's Sarcoma-Associated Herpesvirus K-Rta Exhibits SUMO-Targeting Ubiquitin Ligase (STUbL) Like Activity and Is Essential for Viral Reactivation

The small ubiquitin-like modifier (SUMO) is a protein that regulates a wide variety of cellular processes by covalent attachment of SUMO moieties to a diverse array of target proteins. Sumoylation also plays an important role in the replication of many viruses. Previously, we showed that Kaposi'...

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Detalhes bibliográficos
Main Authors: Izumiya, Yoshihiro, Kobayashi, Keisuke, Kim, Kevin Y., Pochampalli, Mamata, Izumiya, Chie, Shevchenko, Bogdan, Wang, Don-Hong, Huerta, Steve B., Martinez, Anthony, Campbell, Mel, Kung, Hsing-Jien
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749962/
https://ncbi.nlm.nih.gov/pubmed/23990779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003506
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